| 학회 |
한국고분자학회 |
| 학술대회 |
2013년 가을 (10/11 ~ 10/12, 창원컨벤션센터) |
| 권호 |
38권 2호 |
| 발표분야 |
신진연구자 특별 심포지움 |
| 제목 |
Self-assembled Nucleic Acid Biomaterials for Biomedical applications |
| 초록 |
The safe and effective delivery of nucleic acid drugs is a critical and challenging issue that impacts clinical translation of RNA or DNA as a therapeutic. Here we report a new materials concept that combines carrier and cargo: nucleic acid polymers that essentially assemble to form their own means of delivery – nucleic acid-based microstructures. A new method for creating polymerized DNA or RNA is used to generate pre-programmed polymeric DNA or RNA sequences that spontaneously assemble into nanoscale pleated sheets that form a sponge-like RNA microsphere and DNA hydrogel. These nucleic acid biomaterials are applicable for delivering small interference RNA or small drugs such as chemotherapy drugs. |
| 저자 |
이종범 |
| 소속 |
서울시립대 |
| 키워드 |
Nucleic Acid; DNA; RNA
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| E-Mail |
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