| 초록 |
The control of ice recrystallization is very important in cryo-technological fields. Ice recrystallization inhibition (IRI) compounds are therefore designed to limit the growth of ice crystals and control the crystal shape. To improve the IRI activity of cryo-systems, various synthetic polymers such as biomimetic polypeptides from polar fish, facially amphiphilic polymers, polyampholytes, poly(vinyl alcohol) derivatives, and block copolymers with hydrophilic-hydrophobic balance have been developed. Herein, poly(L-alanine-co-L-lysine) (PAK) was shown to exhibit a similar IRI activity to that of PVA. Furthermore, neither poly(L-alanine-co-L-aspartic acid) (PAD) nor poly(ethylene glycol) (PEG) with a similar molecular weight provided any significant IRI activity. These results suggest that PAK is an important compound with superior IRI activity, and that this activity is dependent upon the functional groups and secondary structure of the polypeptides. |
