| 학회 |
한국고분자학회 |
| 학술대회 |
2010년 가을 (10/07 ~ 10/08, 대구 EXCO) |
| 권호 |
35권 2호 |
| 발표분야 |
의료용 고분자 |
| 제목 |
Self-Assembled Brush Polymers with Glycine Derivatives and Its Biocompatibility |
| 초록 |
We have synthesized brush polymers with various glycine derivatives as the end groups of their long alkyl bristles. Interestingly, the thin films of these brush polymers exhibit different molecular multi-layer structures that arise through the efficient self-assembly of the bristles with glycine derivative end groups. These brush polymer films have hydrophilic surfaces and exhibit some water sorption. The extent of the water sorption by these films depends upon the nature of the glycine derivatives in the bristle end. These films not only repel fibrinogen molecules and platelets from their surfaces, but also have high resistance to bacterial adherence. These brush polymers have potential uses in biomedical applications including medical devices, especially blood contacting devices such as catheters, stents, blood vessels, and biosensors, due to their enhanced biocompatibility and the reduced possibility of post-operative infection. |
| 저자 |
정정운1, 이문호2, 박삼대2, 김동민2, 김진철2, 노예철2, 안병철2, 권원상2, 김경태2, 김미희2, 고용기2, 정성민2, 최준만2
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| 소속 |
1포항공과 대, 2포항공과대 |
| 키워드 |
브러쉬 고분자; 생체적합성; 글리신 유도체
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| E-Mail |
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