| 학회 |
한국고분자학회 |
| 학술대회 |
2010년 봄 (04/08 ~ 04/09, 대전컨벤션센터) |
| 권호 |
35권 1호 |
| 발표분야 |
의료용 고분자 부문위원회 |
| 제목 |
Aptamer functionalized single-walled carbon nanotube film biosensor |
| 초록 |
Aptamer functionalized single-walled carbon nanotube (SWNT) film was successfully developed for field effect transistor (FET) biosensor applications. The SWNT was surface-modified to introduce carboxyl groups in the strong acidic solution and grafted with anti-thrombin aptamer as a model aptamer by amide bond formation. The SWNT aptasensor was successfully applied to real-time electrical detection of thrombin samples down to the concentration of 7 pM. The response time in current change was extraordinarily fast within a minute. The novel SWNT FET aptasensor with a high specificity and a short response time will be investigated further for diagnostic applications. |
| 저자 |
고은지, 한세광, 김기수, 안태창, 임근배
|
| 소속 |
포항공과대 |
| 키워드 |
Aptamer; Carbon nanotubes; Thrombin; FET; Biosensor
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| E-Mail |
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