| 학회 |
한국고분자학회 |
| 학술대회 |
2012년 봄 (04/12 ~ 04/13, 대전컨벤션센터) |
| 권호 |
37권 1호 |
| 발표분야 |
기능성 고분자 |
| 제목 |
Photo-responsive egg PC liposome coated with HmPVA/EPC conjugate |
| 초록 |
Photo-responsive egg PC liposome was prepared by coating the surface of egg yolk phosphatidylcholine (egg PC) liposomes with hydrophobically modified poly(vinylalcohol)-epoxypropoxycoumarin conjugate (HmPVA-EPC). Decanoyl chloride (DC) was used as a hydrophobic chain for the hydrophobic modification of PVA. The critical micelle concentration (CMC) determined by a fluorescence method using pyrene as a hydrophobic fluorescent probe. The ratio of the intensities at 372 and 383 nm (I372/I383) were then analyzed to determine CMC. EPC shows a photo reactivity under UV irradiation. Under irradiation of the light wavelength at 254nm (6W) for 3hr, EPC was dimeriazed through the formation of cyclobutane bridges. The release of 5(6)-carboxyfluorescein (CF) from egg PC liposome coated with HmPVA/EPC was enhanced by irradiation of λ = 254 nm (6W), possibly due to the photo-dedimerization of epoxypropoxy coumarin residues of the HmPVA. |
| 저자 |
서희진, 목은영, 김진철
|
| 소속 |
강원대 |
| 키워드 |
Egg PC; liposome; PVA; Coumarin
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| E-Mail |
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