| 학회 |
한국화학공학회 |
| 학술대회 |
2017년 가을 (10/25 ~ 10/27, 대전컨벤션센터) |
| 권호 |
23권 2호, p.2194 |
| 발표분야 |
촉매 및 반응공학 |
| 제목 |
Organocatalysis for Synthesizing Druggable Chemicals: Trial & Error |
| 초록 |
With the generation of harmful side products, high E-factor of pharmaceutical industry is an important problem to be overcame. Even though catalysis can be a solution to reduce cost (economical & safety control) as well as E-factor, heavy metals as major powerful catalysts strictly have applied to pharmaceutical industry due to toxicity of a residual metal. Until today, while tremendous organcatalysts for druggable chemicals strongly have been developed in academia, they shows very limited application to industry. This presentation consists of three parts: (1) concise view of asymmetric PTC (phase-transfer catalysis) as a successful case, (2) jumping history from PTC to iodine chemistry, and (3) my current research on DFT based hypervalent iodine catalysis. |
| 저자 |
김미현1, 박형근2, 김 강1, Arramshetti Venkanna1, Zakir Ullah1, Sualiha Afzal1
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| 소속 |
1가천대 약학대, 2서울대 약학대 |
| 키워드 |
촉매 및 반응공학 |
| E-Mail |
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| VOD |
VOD 보기 |
| 원문파일 |
초록 보기 |
