화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2015년 가을 (11/04 ~ 11/06, 제주국제컨벤션센터(ICCJEJU))
권호 19권 2호
발표분야 생체재료_포스터
제목 Soft and Instrumented Cell-Culture Platform for Monitoring and Transfer Printing of Cell Sheets
초록 A multifunctional, soft cell-culture platform equipped with ultrathin stretchable electronics can allow in vitro physiological monitoring of cells prior to their in vivo tissue regeneration applications. In this study, we present an instrumented and soft electronic cell-culture platform composed of nanomembrane stretchable sensors and graphene-nanoribbons cell aligners on a compliant elastomeric substrate. This platform enables cellular alignments and continuous monitoring of physiological characteristics of plated cells in proliferation and differentiation. Stretchable electronic platform is also successfully applied as an in vitro muscle-on-a-chip testing platform and demonstrated for scaffold-free cell sheet transfer printing techniques. We believe our soft electronic platform will permit real-time monitoring of cellular phenotype, and will also provide rational strategies for cell sheet-based tissue engineering.
저자 김대형, 김석주
소속 서울대
키워드 Flexible and stretchable electronics; Cell-culture platform; Transfer printing
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