화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2009년 가을 (10/08 ~ 10/09, 광주과학기술원 오룡관)
권호 34권 2호
발표분야 고분자 합성
제목 Biological-synthetic polymer polypeptide conjugate hybrid materials and the fabrication of nanomaterials.
초록 Proteinpolymer conjugates are an important biomaterial for a wide range of applications in the areas of medicine and biotechnology. With the advent of new controlled/‘living’ polymerization techniques, the use of protein-reactive initiators to form well-defined polymers is now possible. The preparation of well-defined materials from synthetic polypeptides is now feasible due to the development of initiators that allow the ring-opening polymerization of α-amino acid-N-carboxyanhydrides. The versatility of this polymerization reaction, in particular the ability to incorporate a large variety of amino acid monomers, both natural and synthetic, results in unprecedented flexibility of molecular design. Recently the use of protein macroinitiators to prepare proteinpolymer conjugates in situ has also been described. Here we report the design and synthesis of a series of synthetic polymer polypeptide materials and their self-assembly behavior to form diverse nanomaterials.
저자 허아영, 신남호, 이해청, 김일, 유리 쉬프노브, 하창식
소속 부산대
키워드 Hybrid materials; Nanomaterials; Polypeptide; Self-assembly
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