초록 |
The development of medical multifunctional coatings has been actively studied aiming to reduction of the economic burden and improvement of the efficiency of treatment. In this study, polysilsesquioxane (PSQ)-based nano coatings were fabricated to enhance the durability and antimicrobial effect of dental orthodontic appliances. PSQ is an organic-inorganic hybrid material that can be created as a material having desired functions by introducing various functional groups on siloxane network. We synthesized well-defined PSQ containing quaternary ammonium and long alkyl chain leading to lysis of bacterial membrane by adjusting the amount of water, catalyst, and reaction time in sol-gel reaction. When this PSQ was coated on the dental material PETG substrate, the S. mutans were reduced by 70% and the mechanical strength was remarkably enhanced. The properties of the coatings were also maintained after evaluation of stability in harsh conditions simulating the oral environment. |