| 초록 |
In this study a platform Escherichia coli strain for the productions of short-chain alkanes (gasoline), free fatty acids (FFAs), fatty esters, and fatty alcohols through the fatty acyl-[acyl carrier protein (ACP)] to fatty acid to fatty acyl-CoA pathway was successfully developed. Series of genes were deleted or overexpressed. Consequently, the engineered E. coli strain could produce up to 580.8 mg/L of short chain alkanes. [This work was supported by the Advanced Biomass Research and Development Center of Korea (NRF-2010-0029799) through the Global Frontier Research Program of the Ministry of Science, ICT and Future Planning (MSIP) through the National Research Foundation (NRF). Systems metabolic engineering work was supported by the Technology Development Program to Solve Climate Changes on Systems Metabolic Engineering for Biorefineries (NRF-2012-C1AAA001-2012M1A2A2026556) by MSIP through NRF]. |
