| 학회 |
한국고분자학회 |
| 학술대회 |
2016년 봄 (04/06 ~ 04/08, 대전컨벤션센터) |
| 권호 |
41권 1호 |
| 발표분야 |
의료용 고분자 부문위원회 I |
| 제목 |
Surface micropatterning on nanofiber using femtosecond laser ablation technique for developing the biomimic structure and function of native endothelium. |
| 초록 |
Endothelium, inner layer of blood vessel, interacts directly with blood components. In particular, native endothelium builds elongated structure which induces special interaction properties with blood components such as monocyte adhesion concerned with immune reaction. In this study, we developed elongated monolayer of endothelial cells similar to native tissue by using micropatterned nanofiber scaffolds. The micropatterned nanofibers were fabricated by using femtosecond laser ablation technique. The fiber guides the endothelial cell migration for alignment, and thus patterned nanofiber regulated not only the elongation of endothelial layer, but also the expression of specific vessel function like monocyte adhesion. Collectively, micropatterning skills using laser ablation can be helpful to further study of artificial endothelium formation and vascular graft. |
| 저자 |
신혁준, 신흥수, 신영민, sajeesh kumar, taufiq ahmad, 이진규
|
| 소속 |
한양대 |
| 키워드 |
elongation of Endothelium |
| E-Mail |
|
