| 학회 |
한국고분자학회 |
| 학술대회 |
2008년 가을 (10/09 ~ 10/10, 일산킨텍스) |
| 권호 |
33권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 |
| 제목 |
Self-assemblies from poly(amino acid)-based amphiphilic graft copolymer for transdermal drug delivery |
| 초록 |
Polymeric self-assemblies from amphiphilic poly(amino acid)-based graft copolymer were studied for transdermal drug delivery. In this study self-assemblies with diverse morphology have been prepared and studied. Molecular characteristics of synthesized graft copolymer were characterized 1H-NMR and FT-IR. Self-assembling behavior was studied with dynamic light scattering (DLS), transmission elelctron microscope (TEM) and fluorescence spectroscope. In addition, the feasibility of utilizing these self-assemblies as a transdermal drug carrier was evaluated by using Franz cell diffusion and characterized with confocal laser scanning microscopy (CLSM) as well as fluorescence spectroscopy. |
| 저자 |
정보경1, 심은송이2, 박정환1, 김종득2
|
| 소속 |
1한국과학기술원, 2생명화학공학과 |
| 키워드 |
transdermal delivery; poly(amino acid); skin permeability
|
| E-Mail |
|
