화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2018년 봄 (04/04 ~ 04/06, 대전컨벤션센터)
권호 43권 1호
발표분야 기능성 고분자
제목 Fabrication of phenylboronic acid-containing glucose sensor using quaternary ammonium monomer for enhancement of sensitivity at physiological pH
초록 Recently, stimuli-responsive photonic crystal hydrogel sensor is gaining a lot of attention. Hydrogel sensor differs from the complex electrochemical detection method by being able to easily sense the analyte materials with naked eyes through diffraction phenomenon. The volume of a hydrogel is changed by external stimulus. Therefore, it works as the colorimetric sensor based on "Bragg's law". In this study, we developed method that rapid fabrication process for glucose sensor. Glucose and phenylboronic acid(PBA) combine to form negative charge at pH9. The PBA containing hydrogel swells due to repulsive force between the negative charges. However, at pH 7.4, the swelling is weak due to low equilibrium constant for association reaction of glucose and PBA. We fabricated the glucose, in which we copolymerized HEMA and quaternary ammonium monomer. The sensor showed an increased sensing ability at pH 7.4.
저자 김동연1, 이원목2
소속 1엔게인, 2세종대
키워드 hydrogel; Inverse opal; glucose; sensor;
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