초록 |
Recently, stimuli-responsive photonic crystal hydrogel sensor is gaining a lot of attention. Hydrogel sensor differs from the complex electrochemical detection method by being able to easily sense the analyte materials with naked eyes through diffraction phenomenon. The volume of a hydrogel is changed by external stimulus. Therefore, it works as the colorimetric sensor based on "Bragg's law". In this study, we developed method that rapid fabrication process for glucose sensor. Glucose and phenylboronic acid(PBA) combine to form negative charge at pH9. The PBA containing hydrogel swells due to repulsive force between the negative charges. However, at pH 7.4, the swelling is weak due to low equilibrium constant for association reaction of glucose and PBA. We fabricated the glucose, in which we copolymerized HEMA and quaternary ammonium monomer. The sensor showed an increased sensing ability at pH 7.4. |