| 초록 |
The carbon dot/hemoglobin (CD/Hb) complex has been used as a bio-receptor in an optical sensor to detect cholesterol. This cholesterol optical sensor has been established through fluorescence enhancement of the quenched CD in the CD/Hb complex. The quenching process of the CD/Hb complex happened via interactions between CD and Hb, and the release of CD from the CD/Hb complex is because the hydrophobic interaction between Hb and cholesterol is more favorable than the interaction between CD and Hb in the CD/Hb complex. The CD/Hb complex enabled selective detection of cholesterol with a linear range from 0 – 800 µM, a limit of detection of 56 µM, and response time of 5 minutes. As compared with another cholesterol sensors, the CD/Hb complex-based biosensor is simple, highly sensitive, selective, rapid, eco-friendly, and cost effective for cholesterol detection in both the biological and environmental samples. |
