화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2010년 가을 (10/27 ~ 10/29, 대전컨벤션센터)
권호 14권 2호
발표분야 콜로이드 계면화학을 이용한 최근 Biotechnology 연구개발 동향
제목 Pluronic-based nano-carriers for delivery and imaging
초록 Pluronic-based nano-carriers with good biocompatibility were prepared by photo-crosslinking diacrylated pluronic without using an organic dispersion phase. Due to the change in hydrophobicity of pluronic by temperature, these nano-carriers show a huge thermo-sensitive volume change, which can be used to load target drugs easily and efficiently. Chitosan conjugation to the nano-carriers significantly enhanced long term circulation and preferential localization in tumor.
Acknowledgement: Basic Science Research Program through NRF, MEST, Korea (R15-2008-006-02002-0).
저자 태기융
소속 광주과학기술원
키워드 Pluronic; nano-carriers; dds
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