| 학회 |
한국공업화학회 |
| 학술대회 |
2014년 가을 (11/12 ~ 11/14, 엑스코(대구)) |
| 권호 |
18권 2호 |
| 발표분야 |
콜로이드계면화학-포스터 |
| 제목 |
Biomimetic self-assembly of an novel amphiphilic polyaspartamide nanocell |
| 초록 |
Nanosized self-aggregates with various morphologies are being increasingly studied for targeted delivery of diagnostic and therapeutic molecules. Therefore, this study presents synthesis of an amphiphilic polyaspartamide copolymer grafted with porphyrin molecules that can form micelle-like self-aggregates in an aqueous solution. Increasing the degree of substitution of porphyrin molecules drives the polymer to self-assemble into a highly ordered packing structure. Further introduction of the metal ions into the packing structure leads to a significant increase in the uptake of oxygen molecules. The results will serve to improve the efficiency of targeted delivery for a molecular ultrasound imaging with various biomedical modalities. |
| 저자 |
조윤나, 김희진, 조성우, 이솔이, 정재현
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| 소속 |
숭실대 |
| 키워드 |
polyaspartamide; self-assembly; porphyrin
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| E-Mail |
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