| 학회 |
한국고분자학회 |
| 학술대회 |
2009년 가을 (10/08 ~ 10/09, 광주과학기술원 오룡관) |
| 권호 |
34권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 |
| 제목 |
Drug release behaviors of mineralized hyaluronic acid-based hydrogels for bone tissue engineering |
| 초록 |
Growing evidence show that three-dimensional (3D) environment reveals fundamental mechanisms of cell function and that 3D culture system in vitro can facilitate the understanding of structurefunction relationship in normal and pathological conditions. The development of hydrogels offers new opportunities not only for tissue engineering but also for setting up culture systems in vitro that recapitulate the 3D organization and the differentiated function of these tissues. This study aims to develop a biomineralized hydrogel system can serve as scaffolds promoting bone repair and regeneration. Biomineralization is an important natural phenomenon in bone, teeth, and shell formation. We prepared biomineralized hyaluronic acid-based hydrogels to apply biomimetic strategies to develop novel scaffold materials for bone tissue engineering. The physicochemical characteristics, drug release kinetics and cytotoxicity of biomineralized hyaluronic acid-based hydrogels were investigated |
| 저자 |
김소연, 이수지
|
| 소속 |
충남대 |
| 키워드 |
hydrogel; tissue engineering; mineralization
|
| E-Mail |
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