화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2011년 가을 (10/06 ~ 10/07, 김대중 컨벤션센터)
권호 36권 2호
발표분야 의료용 고분자 부문위원회
제목 Preparation and Characterization of Deoxycholic acid conjugated Chitosan oligosaccharide for thermosensitive nanoparticles
초록 To develop the nanoparticle of thermosensitive based on Chitosan oligosaccharide(COS). COS was chemically modified with Deoxycholic acid(DA) which in one of bile acid as a hydrophobic group. The conjugated thermosensitive moiety as an PEG-PPG diblock copolymer CD nanoparticles (CD-PEGPG) were prepared. The structure was investigated by Fourier transform infrared (FT-IR) and ¹H Nuclear magnetic resonance (¹H-NMR), Particle formation was confirmed to become by Transmission electron microscopy (TEM), Electrophoretic LS spectrophotometer (ELS). The Result synthesised thermosensitive nanoparticle was comfirmed sucessful.
저자 김태훈, 김민성, 장재영, 박준규, 남정표, 김원석, 최창용, 장미경, 나재운
소속 순천대
키워드 PEG-PPG; Chitosan Oligosccharide; Deoxycholic acid; thermosensitive moiety; hydrophobic moiety
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