학회 |
한국고분자학회 |
학술대회 |
2011년 가을 (10/06 ~ 10/07, 김대중 컨벤션센터) |
권호 |
36권 2호 |
발표분야 |
의료용 고분자 부문위원회 |
제목 |
Preparation and Characterization of Deoxycholic acid conjugated Chitosan oligosaccharide for thermosensitive nanoparticles |
초록 |
To develop the nanoparticle of thermosensitive based on Chitosan oligosaccharide(COS). COS was chemically modified with Deoxycholic acid(DA) which in one of bile acid as a hydrophobic group. The conjugated thermosensitive moiety as an PEG-PPG diblock copolymer CD nanoparticles (CD-PEGPG) were prepared. The structure was investigated by Fourier transform infrared (FT-IR) and ¹H Nuclear magnetic resonance (¹H-NMR), Particle formation was confirmed to become by Transmission electron microscopy (TEM), Electrophoretic LS spectrophotometer (ELS). The Result synthesised thermosensitive nanoparticle was comfirmed sucessful. |
저자 |
김태훈, 김민성, 장재영, 박준규, 남정표, 김원석, 최창용, 장미경, 나재운
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소속 |
순천대 |
키워드 |
PEG-PPG; Chitosan Oligosccharide; Deoxycholic acid; thermosensitive moiety; hydrophobic moiety
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E-Mail |
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