| 학회 |
한국공업화학회 |
| 학술대회 |
2011년 가을 (11/02 ~ 11/04, 경원대학교) |
| 권호 |
15권 2호 |
| 발표분야 |
정밀화학 |
| 제목 |
PEG PPG grafted thermosensitive nanoparticles composed of deoxycholic acid modified chitosan oligosccharide |
| 초록 |
To develop the nanoparticle of thermosensitive based on Chitosan oligosaccharide(COS). COS was chemically modified with Deoxycholic acid(DA) which in one of bile acid as a hydrophobic group. The conjugated thermosensitive moiety as an PEG-PPG diblock copolymer CD nanoparticles (CD-PEGPG) were prepared. The structure was investigated by Fourier transform infrared (FT-IR), and ¹H Nuclear magnetic resonance (¹H-NMR), Particle formation was confirmed to become by Transmission electron microscopy (TEM), Electrophoretic LS spectrophotometer (ELS). The critical micellization concentration (CMC) of CDPEGPG nanoparticle in distilled water was determined. The Result synthesised thermosensitive nanoparticle was comfirmed sucessful. |
| 저자 |
김태훈, 김민성, 장재영, 남정표, 박준규, 김원석, 최창용, 장미경, 나재운
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| 소속 |
순천대 |
| 키워드 |
PEG-PPG; COS; Deoxycholic acid; therosensitive moiety; hydrophobic moiety
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| E-Mail |
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