화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2015년 가을 (11/04 ~ 11/06, 제주국제컨벤션센터(ICCJEJU))
권호 19권 2호
발표분야 생체재료_포스터
제목 In Vitro and In Vivo Photothermal Cancer Therapy with pH Tunable Bio-imaging by Using IR825 Integrated Fluorescence Nanoparticles
초록 We report a combined diagnostic fluorescence for bioimaging and therapeutic fluorescence for photothermal therapy (PTT) within an integrate hybrid nanoparticles can simultaneously and accurately diagnosis and ablates the tumor. This new class triggered photothermal therapeutic agents for pH responsive cancer cells target bio-imaging constructed using near-infrared dye (NIR) IR825, polymer conjugated anchored reduced graphene oxide (rGO) hybrid nanoparticles. Using hybrid nanoparticles administered PTT agents, the time-dependent in vivo tumor accumulated hybrid nanoparticles generated require photothermal heat, which caused dominant suppression of tumor growth. The ability to maximize tumor therapy and to monitor treatment condition in target area explores an appealing interest for the successful application of photothermal therapy. This was supported by Korea National University of Transportation in 2015.
저자 이기백, 박성영, 강은비
소속 한국교통대
키워드 Bioimaging; Photothermal therapy; rGO; hyaluronic acid; IR825
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