화학공학소재연구정보센터
학회 한국화학공학회
학술대회 2017년 가을 (10/25 ~ 10/27, 대전컨벤션센터)
권호 23권 2호, p.2152
발표분야 재료
제목 Synthesis of Dual-Color-Emitting Carbon Nanodots via Surface Modification with 4-Octyloxyaniline for Multicolor Bioimaging and Optogenetic Control of Ion Channels
초록 The electronic structure engineering of carbon nanodots (CNDs) has been one of the great issue for their various fields of applications. Here, we have developed intrinsically multicolor-emitting CNDs which emit two distinct colors via the surface electronic structure engineering with 4-octyloxyaniline. The so-called dual-color-emitting CNDs (DC-CNDs) could be stably encapsulated within water-soluble poly(styrene-co-maleic anhydride) (PSMA) enabling biomedical applications to in vitro and in vivo dual-color bioimaging and optogenetics. In vivo optical imaging could visualize the biodistribution of intravenously injected DC-CNDs@PSMA. Moreover, DC-CNDs could be successfully exploited for optogenetic applications via the wavelength-dependent activation of ion channels. As a new type of fluorophore, DC-CNDs offer a big insight into the design of multicolor-emitting materials for various optical and biomedical applications.
저자 박윤상1, 김혜민1, 백송은1, 한슬기1, 정두엽1, 이시우2, 권우성2
소속 1포항공과대, 2숙명여자대
키워드 화공소재 전반
E-Mail
원문파일 초록 보기