| 학회 |
한국공업화학회 |
| 학술대회 |
2013년 봄 (05/01 ~ 05/03, ICC JEJU) |
| 권호 |
17권 1호 |
| 발표분야 |
포스터-생물공학 |
| 제목 |
In vitro investigation on the osteoblastic responses to alendronate-loaded inorganic surface |
| 초록 |
It is evident that surface modification method is still important since it is material surface which directly contacts with physiological environment. In this study, we developed a method of synthesizing the calcium phosphate film which displays an outstanding biocompatibility and reproducibility. Alendronate (ALD) is a member of bisphosphonate family which is approved by FDA for the treatment of osteoporosis. We investigated a interaction between the drug and the film. Osteoblastic cell-lines such as MG63 and SaOS2, were used to examine the cellular proliferation and differentiation. The result demonstrated that the calcium phosphate film can be a potential candidate for drug delivery. |
| 저자 |
강민지, 신지영, 김주승, 백운용, 임희정, 이우걸
|
| 소속 |
단국대 |
| 키워드 |
Calcium phosphate film; alendronate; bisphosphonate; osteoblast
|
| E-Mail |
|
