| 학회 |
한국고분자학회 |
| 학술대회 |
2017년 가을 (10/11 ~ 10/13, 제주컨벤션센터) |
| 권호 |
42권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 I |
| 제목 |
Effect of low Intensity Pulsed Ultrasound on Hydrogels for Bone Regeneration |
| 초록 |
Ultrasound or the application of acoustic energy is a minimally invasive technique that has been used in diagnostic, surgical, imaging, and therapeutic applications. Low-intensity pulsed ultrasound (LIPUS) has been used to convert physical stimuli into biochemical stimuli in the body to accelerate bone fracture recovery. In this study, in situ-gelling alginate, hyaluronic acid, and their mixture hydrogels were injected into rat skull bone defect sites and applied the LIPUS to investigate the effect of ultrasound stimulation on the hydrogels for bone regeneration. The bone regeneration among the hydrogels with or without ultrasound stimulation was evaluated using Micro-CT and Masson’s trichrome staining. From the results, it was observed that the alginate/hyaluronic acid mixture (1:1) hydrogel group with ultrasound stimulation was effective for bone regeneration than other groups. |
| 저자 |
김세현1, 김태호1, 김호용2, 오세행2, 이진호1
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| 소속 |
1한남대, 2단국대 |
| 키워드 |
ultrasound; hydrogel; bone regenration; physical stimuli
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| E-Mail |
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