화학공학소재연구정보센터
검색결과 : 12건
No. Article
1 Hiding in Plain Sight: The Bimetallic Magnesium Covalent Bond in Enzyme Active Sites
Perera L, Beard WA, Pedersen LG, Wilson SH
Inorganic Chemistry, 56(1), 313, 2017
2 Uncovering the polymerase-induced cytotoxicity of an oxidized nucleotide
Freudenthal BD, Beard WA, Perera L, Shock DD, Kim T, Schlick T, Wilson SH
Nature, 517(7536), 635, 2015
3 Structural Comparison of DNA Polymerase Architecture Suggests a Nucleotide Gateway to the Polymerase Active Site
Wu S, Beard WA, Pedersen LG, Wilson SH
Chemical Reviews, 114(5), 2759, 2014
4 Optimal and Variant Metal-Ion Routes in DNA Polymerase beta's Conformational Pathways
Li YL, Freudenthal BD, Beard WA, Wilson SH, Schlick T
Journal of the American Chemical Society, 136(9), 3630, 2014
5 Amino Acid Substitution in the Active Site of DNA Polymerase beta Explains the Energy Barrier of the Nucleotidyl Transfer Reaction
Batra VK, Perera L, Lin P, Shock DD, Beard WA, Pedersen LC, Pedersen LG, Wilson SH
Journal of the American Chemical Society, 135(21), 8078, 2013
6 Halogenated beta,gamma-Methylene- and Ethylidene-dGTP-DNA Ternary Complexes with DNA Polymerase beta: Structural Evidence for Stereospecific Binding of the Fluoromethylene Analogues
Batra VK, Pedersen LC, Beard WA, Wilson SH, Kashemirov BA, Upton TG, Goodman MF, McKenna CE
Journal of the American Chemical Society, 132(22), 7617, 2010
7 (R)-beta,gamma-fluoromethylene-dGTP-DNA ternary complex with DNA polymerase beta
McKenna CE, Kashemirov BA, Upton TG, Batra VK, Goodman MF, Pedersen LC, Beard WA, Wilson SH
Journal of the American Chemical Society, 129(50), 15412, 2007
8 Structure and mechanism of DNA polymerase beta
Beard WA, Wilson SH
Chemical Reviews, 106(2), 361, 2006
9 Determination of lysine pK values using [5-C-13]lysine: Application to the lyase domain of DNA pol beta
Gao GH, Prasad R, Lodwig SN, Unkefer CJ, Beard WA, Wilson SH, London RE
Journal of the American Chemical Society, 128(25), 8104, 2006
10 Critical role of magnesium ions in DNA polymerase beta's closing and active site assembly
Yang LJ, Arora K, Beard WA, Wilson SH, Schlick T
Journal of the American Chemical Society, 126(27), 8441, 2004