화학공학소재연구정보센터
검색결과 : 23건
No. Article
1 Random epigenetic modulation of CHO cells by repeated knockdown of DNA methyltransferases increases population diversity and enables sorting of cells with higher production capacities
Weinguny M, Eisenhut P, Klanert G, Virgolini N, Marx N, Jonsson A, Ivansson D, Lovgren A, Borth N
Biotechnology and Bioengineering, 117(11), 3435, 2020
2 Epigenetic regulation of gene expression in Chinese Hamster Ovary cells in response to the changing environment of a batch culture
Hernandez I, Dhiman H, Klanert G, Jadhav V, Auer N, Hanscho M, Baumann M, Esteve-Codina A, Dabad M, Gomez J, Alioto T, Merkel A, Raineri E, Heath S, Rico D, Borth N
Biotechnology and Bioengineering, 116(3), 677, 2019
3 Genetic engineering approaches to improve posttranslational modification of biopharmaceuticals in different production platforms
Amann T, Schmieder V, Kildegaard HF, Borth N, Andersen MR
Biotechnology and Bioengineering, 116(10), 2778, 2019
4 Karyotype variation of CHO host cell lines over time in culture characterized by chromosome counting and chromosome painting
Vcelar S, Jadhav V, Melcher M, Auer N, Hrdina A, Sagmeister R, Heffner K, Puklowski A, Betenbaugh M, Wenger T, Leisch F, Baumann M, Borth N
Biotechnology and Bioengineering, 115(1), 165, 2018
5 A reference genome of the Chinese hamster based on a hybrid assembly strategy
Rupp O, MacDonald ML, Li SZ, Dhiman H, Polson S, Griep S, Heffner K, Hernandez I, Brinkrolf K, Jadhav V, Samoudi M, Hao HP, Kingham B, Goesmann A, Betenbaugh MJ, Lewis NE, Borth N, Lee KH
Biotechnology and Bioengineering, 115(8), 2087, 2018
6 Preselection of recombinant gene integration sites enabling high transcription rates in CHO cells using alternate start codons and recombinase mediated cassette exchange
Baumann M, Gludovacz E, Sealover N, Bahr S, George H, Lin N, Kayser K, Borth N
Biotechnology and Bioengineering, 114(11), 2616, 2017
7 Comprehensive Genome and Epigenome Characterization of CHO Cells in Response to Evolutionary Pressures and Over Time
Feichtinger J, Hernandez I, Fischer C, Hanscho M, Auer N, Hackl M, Jadhav V, Baumann M, Krempl PM, Schmidl C, Farlik M, Schuster M, Merkel A, Sommer A, Heath S, Rico D, Bock C, Thallinger GG, Borth N
Biotechnology and Bioengineering, 113(10), 2241, 2016
8 Annotation of additional evolutionary conserved microRNAs in CHO cells from updated genomic data
Diendorfer AB, Hackl M, Klanert G, Jadhav V, Reithofer M, Stiefel F, Hesse F, Grillari J, Borth N
Biotechnology and Bioengineering, 112(7), 1488, 2015
9 Identification of microRNAs specific for high producer CHO cell lines using steady-state cultivation
Maccani A, Hackl M, Leitner C, Steinfellner W, Graf AB, Tatto NE, Karbiener M, Scheideler M, Grillari J, Mattanovich D, Kunert R, Borth N, Grabherr R, Ernst W
Applied Microbiology and Biotechnology, 98(17), 7535, 2014
10 Chinese hamster genome database: An online resource for the CHO community at www.CHOgenome.org
Hammond S, Kaplarevic M, Borth N, Betenbaugh MJ, Lee KH
Biotechnology and Bioengineering, 109(6), 1353, 2012