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Biocatalytic preparation of a chiral synthon for a vasopeptidase inhibitor: enzymatic conversion of N-2-[N-phenylmethoxy)carbonyl] L-homocysteinyl]-L-lysine (1-> 1 ')-disulfide to [4S-(4I,7I,10aJ)] 1-octahydro-5-oxo-4-[phenylmethoxy)carbonyl]amino]-7H-pyrido-[2,1-b] [1,3]thiazepine-7-carboxylic acid methyl ester by a novel L-lysine epsilon-aminotransferase Patel RN, Banerjee A, Nanduri VB, Goldberg SL, Johnston RM, Hanson RL, McNamee CG, Brzozowski DB, Tully TP, Ko RY, LaPorte TL, Cazzulino DL, Swaminathan S, Chen CK, Parker LW, Venit JJ Enzyme and Microbial Technology, 27(6), 376, 2000 |