| 1 |
Structure-Function Analysis of the Extended Conformation of a Polyketide Synthase Module
Li XY, Sevillano N, La Greca F, Deis L, Liu YC, Deller MC, Mathews II, Matsui T, Cane DE, Craik CS, Khosla C
Journal of the American Chemical Society, 140(21), 6518, 2018 |
| 2 |
Mechanism and Stereochemistry of Polyketide Chain Elongation and Methyl Group Epimerization in Polyether Biosynthesis
Xie XQ, Garg A, Khosla C, Cane DE
Journal of the American Chemical Society, 139(8), 3283, 2017 |
| 3 |
Elucidation of the Stereospecificity of C-Methyltransferases from trans-AT Polyketide Synthases
Xie XQ, Khosla C, Cane DE
Journal of the American Chemical Society, 139(17), 6102, 2017 |
| 4 |
Stereospecific Formation of E- and Z-Disubstituted Double Bonds by Dehydratase Domains from Modules 1 and 2 of the Fostriecin Polyketide Synthase
Shah DD, You YO, Cane DE
Journal of the American Chemical Society, 139(40), 14322, 2017 |
| 5 |
Elucidation of the Cryptic Methyl Group Epimerase Activity of Dehydratase Domains from Modular Polyketide Synthases Using a Tandem Modules Epimerase Assay
Xie XQ, Garg A, Khosla C, Cane DE
Journal of the American Chemical Society, 139(28), 9507, 2017 |
| 6 |
The Cytochrome P450-Catalyzed Oxidative Rearrangement in the Final Step of Pentalenolactone Biosynthesis: Substrate Structure Determines Mechanism
Duan L, Jogl G, Cane DE
Journal of the American Chemical Society, 138(38), 12678, 2016 |
| 7 |
Generation of Complexity in Fungal Terpene Biosynthesis: Discovery of a Multifunctional Cytochrome P450 in the Fumagillin Pathway
Lin HC, Tsunematsu Y, Dhingra S, Xu W, Fukutomi M, Chooi YH, Cane DE, Calvo AM, Watanabe K, Tang Y
Journal of the American Chemical Society, 136(11), 4426, 2014 |
| 8 |
Elucidation of the Cryptic Epimerase Activity of Redox-Inactive Ketoreductase Domains from Modular Polyketide Synthases by Tandem Equilibrium Isotope Exchange
Garg A, Xie XQ, Keatinge-Clay A, Khosla C, Cane DE
Journal of the American Chemical Society, 136(29), 10190, 2014 |
| 9 |
Stereochemistry of Reductions Catalyzed by Methyl-Epimerizing Ketoreductase Domains of Polyketide Synthases
You YO, Khosla C, Cane DE
Journal of the American Chemical Society, 135(20), 7406, 2013 |
| 10 |
Coupled Methyl Group Epimerization and Reduction by Polyketide Synthase Ketoreductase Domains. Ketoreductase-Catalyzed Equilibrium Isotope Exchange
Garg A, Khosla C, Cane DE
Journal of the American Chemical Society, 135(44), 16324, 2013 |
