| 1 |
Mutagenesis of an Active-Site Loop in Tryptophan Hydroxylase Dramatically Slows the Formation of an Early Intermediate in Catalysis
Subedi BP, Fitzpatrick PF
Journal of the American Chemical Society, 140(15), 5185, 2018 |
| 2 |
The regulatory domain of human tryptophan hydroxylase 1 forms a stable dimer
Zhang S, Hinck CS, Fitzpatrick PF
Biochemical and Biophysical Research Communications, 476(4), 457, 2016 |
| 3 |
Domain Movements upon Activation of Phenylalanine Hydroxylase Characterized by Crystallography and Chromatography-Coupled Small-Angle X-ray Scattering
Meisburger SP, Taylor AB, Khan CA, Zhang SN, Fitzpatrick PF, Ando N
Journal of the American Chemical Society, 138(20), 6506, 2016 |
| 4 |
Measurement of the Intramolecular Isotope Effect on Aliphatic Hydroxylation by Chromobacterium violaceum Phenylalanine Hydroxylase
Panay AJ, Fitzpatrick PF
Journal of the American Chemical Society, 132(16), 5584, 2010 |
| 5 |
Demonstration of a Peroxide Shunt in the Tetrahydropterin-Dependent Aromatic Amino Acid Monooxygenases
Pavon JA, Fitzpatrick PF
Journal of the American Chemical Society, 131(13), 4582, 2009 |
| 6 |
Spectroscopy and Kinetics of Wild-Type and Mutant Tyrosine Hydroxylase: Mechanistic Insight into O-2 Activation
Chow MS, Eser BE, Wilson SA, Hodgson KO, Hedman B, Fitzpatrick PF, Solomon EI
Journal of the American Chemical Society, 131(22), 7685, 2009 |
| 7 |
Direct spectroscopic evidence for a high-spin Fe(IV) intermediate in tyrosine hydroxylase
Eser BE, Barr EW, Frantorn PA, Saleh L, Bollinger JM, Krebs C, Fitzpatrick PF
Journal of the American Chemical Society, 129(37), 11334, 2007 |
| 8 |
Establishing the kinetic competency of the cationic imine intermediate in nitroalkane oxidase
Valley MP, Tichy SE, Fitzpatrick PF
Journal of the American Chemical Society, 127(7), 2062, 2005 |
| 9 |
Intrinsic isotope effects on benzylic hydroxylation by the aromatic amino acid hydroxylases: Evidence for hydrogen tunneling, coupled motion, and similar reactivities
Pavon JA, Fitzpatrick PF
Journal of the American Chemical Society, 127(47), 16414, 2005 |
| 10 |
Comparison of enzymatic and non-enzymatic nitroethane anion formation: Thermodynamics and contribution of Tunneling
Valley MP, Fitzpatrick PF
Journal of the American Chemical Society, 126(20), 6244, 2004 |
