검색결과 : 34건
No. | Article |
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1 |
Structure-based decoupling of the pro- and anti-inflammatory functions of interleukin-10 Saxton RA, Tsutsumi N, Su LL, Abhiraman GC, Mohan K, Henneberg LT, Aduri NG, Gati C, Garcia KC Science, 371(6535), 1222, 2021 |
2 |
Mutational signature in colorectal cancer caused by genotoxic pks(+)E. coli Pleguezuelos-Manzano C, Puschhof J, Huber AR, van Hoeck A, Wood HM, Nomburg J, Gurjao C, Manders F, Dalmasso G, Stege PB, Paganelli FL, Geurts MH, Beumer J, Mizutani T, Miao Y, van der Linden R, van der Elst S, Garcia KC, Top J, Willems RJL, Giannakis M, Bonnet R, Quirke P, Meyerson M, Cuppen E, van Boxtel R, Clevers H Nature, 580(7802), 269, 2020 |
3 |
Progenitor identification and SARS-CoV-2 infection in human distal lung organoids Salahudeen AA, Choi SS, Rustagi A, Zhu JJ, van Unen V, De La O SM, Flynn RA, Margalef-Catala M, Santos AJM, Ju JH, Batish A, Usui T, Zheng GXY, Edwards CE, Wagar LE, Luca V, Anchang B, Nagendran M, Nguyen K, Hart DJ, Terry JM, Belgrader P, Ziraldo SB, Mikkelsen TS, Harbury PB, Glenn JS, Garcia KC, Davis MM, Baric RS, Sabatti C, Amieva MR, Blish CA, Desai TJ, Kuo CJ Nature, 588(7839), 670, 2020 |
4 |
Immune receptor inhibition through enforced phosphatase recruitment Fernandes RA, Su L, Nishiga Y, Ren JM, Bhuiyan AM, Cheng N, Kuo CJ, Picton LK, Ohtsuki S, Majzner RG, Rietberg SP, Mackall CL, Yin Q, Ali LR, Yang XB, Savvides CS, Sage J, Dougan M, Garcia KC Nature, 586(7831), 779, 2020 |
5 |
Progenitor identification and SARS-CoV-2 infection in human distal lung organoids Salahudeen AA, Choi SS, Rustagi A, Zhu JJ, van Unen V, De La O SM, Flynn RA, Margalef-Catala M, Santos AJM, Ju JH, Batish A, Usui T, Zheng GXY, Edwards CE, Wagar LE, Luca V, Anchang B, Nagendran M, Nguyen K, Hart DJ, Terry JM, Belgrader P, Ziraldo SB, Mikkelsen TS, Harbury PB, Glenn JS, Garcia KC, Davis MM, Baric RS, Sabatti C, Amieva MR, Blish CA, Desai TJ, Kuo CJ Nature, 588(7839), 670, 2020 |
6 |
Immune receptor inhibition through enforced phosphatase recruitment Fernandes RA, Su L, Nishiga Y, Ren JM, Bhuiyan AM, Cheng N, Kuo CJ, Picton LK, Ohtsuki S, Majzner RG, Rietberg SP, Mackall CL, Yin Q, Ali LR, Yang XB, Savvides CS, Sage J, Dougan M, Garcia KC Nature, 586(7831), 779, 2020 |
7 |
Mechanism of homodimeric cytokine receptor activation and dysregulation by oncogenic mutations Wilmes S, Hafer M, Vuorio J, Tucker JA, Winkelmann H, Lochte S, Stanly TA, Prieto KDP, Poojari C, Sharma V, Richter CP, Kurre R, Hubbard SR, Garcia KC, Moraga I, Vattulainen I, Hitchcock IS, Piehler J Science, 367(6478), 643, 2020 |
8 |
Structure and selectivity engineering of the M-1 muscarinic receptor toxin complex Maeda S, Xu J, Kadji FMN, Clark MJ, Zhao JW, Tsutsumi N, Aoki J, Sunahara RK, Inoue A, Garcia KC, Kobilka BK Science, 369(6500), 161, 2020 |
9 |
Structure of the IFN gamma receptor complex guides design of biased agonists Mendoza JL, Escalante NK, Jude KM, Bellon JS, Su L, Horton TM, Tsutsumi N, Berardinelli SJ, Haltiwanger RS, Piehler J, Engleman EG, Garcia KC Nature, 567(7746), 56, 2019 |
10 |
De novo design of potent and selective mimics of IL-2 and IL-15 Silva DA, Yu S, Ulge UY, Spangler JB, Jude KM, Labao-Almeida C, Ali LR, Quijano-Rubio A, Ruterbusch M, Leung I, Biary T, Crowley SJ, Marcos E, Walkey CD, Weitzner BD, Pardo-Avila F, Castellanos J, Carter L, Stewart L, Riddell SR, Pepper M, Bernardes GJL, Dougan M, Garcia KC, Baker D Nature, 565(7738), 186, 2019 |