검색결과 : 15건
| No. | Article |
|---|---|
| 1 |
Forum Drug discovery A question of library design Hajduk PJ Nature, 470(7332), 42, 2011 |
| 2 |
High-level bacterial expression and purification of human SirT2 protein for NMR studies Sun CH, Song DY, Marcotte PA, Richardson PL, Hajduk PJ Protein Expression and Purification, 48(1), 56, 2006 |
| 3 |
ALARM NMR: A rapid and robust experimental method to detect reactive false positives in biochemical screens Huth JR, Mendoza R, Olejniczak ET, Johnson RW, Cothron DA, Liu YY, Lerner CG, Chen J, Hajduk PJ Journal of the American Chemical Society, 127(1), 217, 2005 |
| 4 |
SOS-NMR: A saturation transfer NMR-based method for determining the structures of protein-ligand complexes Hajduk PJ, Mack JC, Olejniczak ET, Park C, Dandliker PJ, Beutel BA Journal of the American Chemical Society, 126(8), 2390, 2004 |
| 5 |
Discovery of a potent, selective protein tyrosine phosphatase 1B inhibitor using a linked-fragment strategy Szczepankiewicz BG, Liu G, Hajduk PJ, Abad-Zapatero C, Pei ZH, Xin ZL, Lubben TH, Trevillyan JM, Stashko MA, Ballaron SJ, Liang H, Huang F, Hutchins CW, Fesik SW, Jirousek MR Journal of the American Chemical Society, 125(14), 4087, 2003 |
| 6 |
Rational design of diflunisal analogues with reduced affinity for human serum albumin Mao HY, Hajduk PJ, Craig R, Bell R, Borre T, Fesik SW Journal of the American Chemical Society, 123(43), 10429, 2001 |
| 7 |
NMR-based screening of proteins containing C-13-labeled methyl groups Hajduk PJ, Augeri DJ, Mack J, Mendoza R, Yang JG, Betz SF, Fesik SW Journal of the American Chemical Society, 122(33), 7898, 2000 |
| 8 |
The use of differential chemical shifts for determining the binding site location and orientation of protein-bound ligands Medek A, Hajduk PJ, Mack J, Fesik SW Journal of the American Chemical Society, 122(6), 1241, 2000 |
| 9 |
Discovery of Potent Nonpeptide Inhibitors of Stromelysin Using SAR by NMR Hajduk PJ, Sheppard G, Nettesheim DG, Olejniczak ET, Shuker SB, Meadows RP, Steinman DH, Carrera GM, Marcotte PA, Severin J, Walter K, Smith H, Gubbins E, Simmer R, Holzman TF, Morgan DW, Davidsen SK, Summers JB, Fesik SW Journal of the American Chemical Society, 119(25), 5818, 1997 |
| 10 |
Stromelysin Inhibitors Designed from Weakly-Bound Fragments - Effects of Linking and Cooperativity Olejniczak ET, Hajduk PJ, Marcotte PA, Nettesheim DG, Meadows RP, Edalji R, Holzman TF, Fesik SW Journal of the American Chemical Society, 119(25), 5828, 1997 |