검색결과 : 13건
No. | Article |
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1 |
Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly Horn-Ghetko D, Krist DT, Prabu JR, Baek K, Mulder MPC, Klugel M, Scott DC, Ovaa H, Kleiger G, Schulman BA Nature, 590(7847), 2021 |
2 |
Manno-epi-cyclophellitols Enable Activity-Based Protein Profiling of Human alpha-Mannosidases and Discovery of New Golgi Mannosidase II Inhibitors Armstrong Z, Kuo CL, Lahav D, Liu B, Johnson R, Beenakker TJM, de Boer C, Wong CS, van Rijssel ER, Debets MF, Florea BI, Hissink C, Boot RG, Geurink PP, Ovaa H, van der Stelt M, van der Marel GM, Codee JDC, Aerts JMFG, Wu L, Overkleeft HS, Davies GJ Journal of the American Chemical Society, 142(30), 13021, 2020 |
3 |
Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity Shin D, Mukherjee R, Grewe D, Bojkova D, Baek K, Bhattacharya A, Schulz L, Widera M, Mehdipour AR, Tascher G, Geurink PP, Wilhelm A, van Noort GJV, Ovaa H, Muller S, Knobeloch KP, Rajalingam K, Schulman BA, Cinatl J, Hummer G, Ciesek S, Dikic I Nature, 587(7835), 657, 2020 |
4 |
Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity Shin D, Mukherjee R, Grewe D, Bojkova D, Baek K, Bhattacharya A, Schulz L, Widera M, Mehdipour AR, Tascher G, Geurink PP, Wilhelm A, van Noort GJV, Ovaa H, Muller S, Knobeloch KP, Rajalingam K, Schulman BA, Cinatl J, Hummer G, Ciesek S, Dikic I Nature, 587(7835), 657, 2020 |
5 |
The Alkyne Moiety as a Latent Electrophile in Irreversible Covalent Small Molecule Inhibitors of Cathepsin K Mons E, Jansen IDC, Loboda J, van Doodewaerd BR, Hermans J, Verdoes M, van Boeckel CAA, van Veelen PA, Turk B, Turk D, Ovaa H Journal of the American Chemical Society, 141(8), 3507, 2019 |
6 |
Rapid Covalent-Probe Discovery by Electrophile-Fragment Screening Resnick E, Bradley A, Gan JR, Douangamath A, Krojer T, Sethi R, Geurink PP, Aimon A, Amitai G, Bellini D, Bennett J, Fairhead M, Fedorov O, Gabizon R, Gan J, Gu JX, Plotnikov A, Reznik N, Ruda GF, Diaz-Saez L, Straub VM, Szommer T, Velupillai S, Zaidman D, Zhang YL, Coker AR, Dowson CG, Barr HM, Wang C, Huber KVM, Brennan PE, Ovaa H, von Delft F, London N Journal of the American Chemical Society, 141(22), 8951, 2019 |
7 |
A Fluorescence Polarization Activity-Based Protein Profiling Assay in the Discovery of Potent, Selective Inhibitors for Human Nonlysosomal Glucosylceramidase Lahav D, Liu B, van den Berg RJBHN, van den Nieuwendijk AMCH, Wennekes T, Ghisaidoobe AT, Breen I, Ferraz MJ, Kuo CL, Wu L, Geurink PP, Ovaa H, van der Marel GA, van der Stelt M, Boot RG, Davies GJ, Aerts JMFG, Overkleeft HS Journal of the American Chemical Society, 139(40), 14192, 2017 |
8 |
Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne Mevissen TET, Kulathu Y, Mulder MPC, Geurink PP, Maslen SL, Gersch M, Elliott PR, Burke JE, van Tol BDM, Akutsu M, El Oualid F, Kawasaki M, Freund SMV, Ovaa H, Komander D Nature, 538(7625), 402, 2016 |
9 |
On Terminal Alkynes That Can React with Active-Site Cysteine Nucleophiles in Proteases Ekkebus R, van Kasteren SI, Kulathu Y, Scholten A, Berlin I, Geurink PP, de Jong A, Goerdayal S, Neefjes J, Heck AJR, Komander D, Ovaa H Journal of the American Chemical Society, 135(8), 2867, 2013 |
10 |
Chemical Evolution of Autotaxin Inhibitors Albers HMHG, Ovaa H Chemical Reviews, 112(5), 2593, 2012 |