화학공학소재연구정보센터
검색결과 : 13건
No. Article
1 Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly
Horn-Ghetko D, Krist DT, Prabu JR, Baek K, Mulder MPC, Klugel M, Scott DC, Ovaa H, Kleiger G, Schulman BA
Nature, 590(7847), 2021
2 Manno-epi-cyclophellitols Enable Activity-Based Protein Profiling of Human alpha-Mannosidases and Discovery of New Golgi Mannosidase II Inhibitors
Armstrong Z, Kuo CL, Lahav D, Liu B, Johnson R, Beenakker TJM, de Boer C, Wong CS, van Rijssel ER, Debets MF, Florea BI, Hissink C, Boot RG, Geurink PP, Ovaa H, van der Stelt M, van der Marel GM, Codee JDC, Aerts JMFG, Wu L, Overkleeft HS, Davies GJ
Journal of the American Chemical Society, 142(30), 13021, 2020
3 Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity
Shin D, Mukherjee R, Grewe D, Bojkova D, Baek K, Bhattacharya A, Schulz L, Widera M, Mehdipour AR, Tascher G, Geurink PP, Wilhelm A, van Noort GJV, Ovaa H, Muller S, Knobeloch KP, Rajalingam K, Schulman BA, Cinatl J, Hummer G, Ciesek S, Dikic I
Nature, 587(7835), 657, 2020
4 Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity
Shin D, Mukherjee R, Grewe D, Bojkova D, Baek K, Bhattacharya A, Schulz L, Widera M, Mehdipour AR, Tascher G, Geurink PP, Wilhelm A, van Noort GJV, Ovaa H, Muller S, Knobeloch KP, Rajalingam K, Schulman BA, Cinatl J, Hummer G, Ciesek S, Dikic I
Nature, 587(7835), 657, 2020
5 The Alkyne Moiety as a Latent Electrophile in Irreversible Covalent Small Molecule Inhibitors of Cathepsin K
Mons E, Jansen IDC, Loboda J, van Doodewaerd BR, Hermans J, Verdoes M, van Boeckel CAA, van Veelen PA, Turk B, Turk D, Ovaa H
Journal of the American Chemical Society, 141(8), 3507, 2019
6 Rapid Covalent-Probe Discovery by Electrophile-Fragment Screening
Resnick E, Bradley A, Gan JR, Douangamath A, Krojer T, Sethi R, Geurink PP, Aimon A, Amitai G, Bellini D, Bennett J, Fairhead M, Fedorov O, Gabizon R, Gan J, Gu JX, Plotnikov A, Reznik N, Ruda GF, Diaz-Saez L, Straub VM, Szommer T, Velupillai S, Zaidman D, Zhang YL, Coker AR, Dowson CG, Barr HM, Wang C, Huber KVM, Brennan PE, Ovaa H, von Delft F, London N
Journal of the American Chemical Society, 141(22), 8951, 2019
7 A Fluorescence Polarization Activity-Based Protein Profiling Assay in the Discovery of Potent, Selective Inhibitors for Human Nonlysosomal Glucosylceramidase
Lahav D, Liu B, van den Berg RJBHN, van den Nieuwendijk AMCH, Wennekes T, Ghisaidoobe AT, Breen I, Ferraz MJ, Kuo CL, Wu L, Geurink PP, Ovaa H, van der Marel GA, van der Stelt M, Boot RG, Davies GJ, Aerts JMFG, Overkleeft HS
Journal of the American Chemical Society, 139(40), 14192, 2017
8 Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne
Mevissen TET, Kulathu Y, Mulder MPC, Geurink PP, Maslen SL, Gersch M, Elliott PR, Burke JE, van Tol BDM, Akutsu M, El Oualid F, Kawasaki M, Freund SMV, Ovaa H, Komander D
Nature, 538(7625), 402, 2016
9 On Terminal Alkynes That Can React with Active-Site Cysteine Nucleophiles in Proteases
Ekkebus R, van Kasteren SI, Kulathu Y, Scholten A, Berlin I, Geurink PP, de Jong A, Goerdayal S, Neefjes J, Heck AJR, Komander D, Ovaa H
Journal of the American Chemical Society, 135(8), 2867, 2013
10 Chemical Evolution of Autotaxin Inhibitors
Albers HMHG, Ovaa H
Chemical Reviews, 112(5), 2593, 2012