| 1 |
Directed evolution of theB. subtilisnitroreductase YfkO improves activation of the PET-capable probe SN33623 and CB1954 prodrug
Rich MH, Sharrock AV, Ashoorzadeh A, Patterson AV, Smaill JB, Ackerley DF
Biotechnology Letters, 43(1), 203, 2021 |
| 2 |
Binding mode of the breakthrough inhibitor AZD9291 to epidermal growth factor receptor revealed
Yosaatmadja Y, Silva S, Dickson JM, Patterson AV, Smaill JB, Flanagan JU, McKeage MJ, Squire CJ
Journal of Structural Biology, 192(3), 539, 2015 |
| 3 |
Characterization of Radicals Formed Following Enzymatic Reduction of 3-Substituted Analogues of the Hypoxia-Selective Cytotoxin 3-Amino-1,2,4-Benzotriazine 1,4-Dioxide (Tirapazamine)
Shinde SS, Maroz A, Hay MP, Patterson AV, Denny WA, Anderson RF
Journal of the American Chemical Society, 132(8), 2591, 2010 |
| 4 |
Spin Trapping of Radicals Other Than the (OH)-O-center dot Radical upon Reduction of the Anticancer Agent Tirapazamine by Cytochrome P-450 Reductase
Shinde SS, Hay MP, Patterson AV, Denny WA, Anderson RF
Journal of the American Chemical Society, 131(40), 14220, 2009 |
