| 1 |
Molecular basis for thermal properties of Streptomyces thermovulgaris fumarase C hinge at hydrophilic amino acids R163, E170 and S347
Lin WJ, Chan M, Goh LL, Sim TS
Applied Microbiology and Biotechnology, 75(2), 329, 2007 |
| 2 |
Pfnek3 functions as an atypical MAPKK in Plasmodium falciparum
Low HY, Lye YM, Sim TS
Biochemical and Biophysical Research Communications, 361(2), 439, 2007 |
| 3 |
Functional analysis, overexpression, and kinetic characterization of pyruvate kinase from Plasmodium falciparum
Chan M, Sim TS
Biochemical and Biophysical Research Communications, 326(1), 188, 2005 |
| 4 |
Characterization of amino acid variation at strategic positions in parasite and human proteases for selective inhibition of falcipains in Plasmodium falciparum
Goh LL, Sim TS
Biochemical and Biophysical Research Communications, 335(3), 762, 2005 |
| 5 |
Homology modeling and mutagenesis analyses of Plasmodium falciparum falcipain 2A: implications for rational drug design
Goh LL, Sim TS
Biochemical and Biophysical Research Communications, 323(2), 565, 2004 |
| 6 |
Soluble expression of a functionally active Plasmodium falciparum falcipain-2 fused to maltose-binding protein in Escherichia coli
Goh LL, Loke P, Singh M, Sim TS
Protein Expression and Purification, 32(2), 194, 2003 |
| 7 |
C-terminus modification of Streptomyces clavuligerus deacetoxycephalosporin C synthase improves catalysis with an expanded substrate specificity
Chin HS, Sim TS
Biochemical and Biophysical Research Communications, 295(1), 55, 2002 |
| 8 |
Replacement of arginine-171 and aspartate-453 in Streptomyces coelicolor malate synthase A by site-directed mutagenesis inactivates the enzyme
Goh LL, Loke P, Sim TS
Applied Microbiology and Biotechnology, 57(3), 363, 2001 |
| 9 |
The invariant F283 and its strategic position in the hydrophobic cleft of Streptomyces jumonjinensis isopenicillin N synthase active site are functionally important
Wong E, Sim J, Sim TS
Biochemical and Biophysical Research Communications, 283(3), 621, 2001 |
| 10 |
Mutation of N304 to leucine in Streptomyces clavuligerus deacetoxycephalosporin C synthase creates an enzyme with increased penicillin analogue conversion
Chin HS, Sim J, Sim TS
Biochemical and Biophysical Research Communications, 287(2), 507, 2001 |
