검색결과 : 14건
No. | Article |
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1 |
Discovery of Lysine-Targeted eIF4E Inhibitors through Covalent Docking Wan XB, Yang TP, Cuesta A, Pang XM, Balius TE, Irwin JJ, Shoichet BK, Taunton J Journal of the American Chemical Society, 142(11), 4960, 2020 |
2 |
Ligand Conformational Bias Drives Enantioselective Modification of a Surface-Exposed Lysine on Hsp90 Cuesta A, Wan XB, Burlingame AL, Taunton J Journal of the American Chemical Society, 142(7), 3392, 2020 |
3 |
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing Gordon DE, Jang GM, Bouhaddou M, Xu JW, Obernier K, White KM, O'Meara MJ, Rezelj VV, Guo JFZ, Swaney DL, Tummino TA, Huttenhain R, Kaake RM, Richards AL, Tutuncuoglu B, Foussard H, Batra J, Haas K, Modak M, Kim M, Haas P, Polacco BJ, Braberg H, Fabius JM, Eckhardt M, Soucheray M, Bennett MJ, Cakir M, McGregor MJ, Li QY, Meyer B, Roesch F, Vallet T, Mac Kain A, Miorin L, Moreno E, Naing ZZC, Zhou Y, Peng SM, Shi Y, Zhang ZY, Shen WQ, Kirby IT, Melnyk JE, Chorba JS, Lou KV, Dai SZA, Barrio-Hernandez I, Memon D, Hernandez-Armenta C, Lyu J, Mathy CJP, Perica T, Pilla KB, Ganesan SJ, Saltzberg DJ, Rakesh R, Liu X, Rosenthal SB, Calviello L, Venkataramanan S, Liboy-Lugo J, Lin YZ, Huang XP, Liu YF, Wankowicz SA, Bohn M, Safari M, Ugur FS, Koh C, Savar NS, Tran QD, Shengjuler D, Fletcher SJ, O'Neal MC, Cai YM, Chang JCJ, Broadhurst DJ, Klippsten S, Sharp PP, Wenzell NA, Kuzuoglu-Ozturk D, Wang HY, Trenker R, Young JM, Cavero DA, Hiatt J, Roth TL, Rathore U, Subramanian A, Noack J, Hubert M, Stroud RM, Frankel AD, Rosenberg OS, Verba KA, Agard DA, Ott M, Emerman M, Jura N, von Zastrow M, Verdin E, Ashworth A, Schwartz O, D'Enfert C, Mukherjee S, Jacobson M, Malik HS, Fujimori DG, Ideker T, Craik CS, Floor SN, Fraser JS, Gross JD, Sali A, Roth BL, Ruggero D, Taunton J, Kortemme T, Beltrao P, Vignuzzi M, Garcia-Sastre A, Shokat KM, Shoichet BK, Krogan NJ Nature, 583(7816), 459, 2020 |
4 |
Broad-Spectrum Kinase Profiling in Live Cells with Lysine-Targeted Sulfonyl Fluoride Probes Zhao Q, Ouyang XH, Wan XB, Gajiwala KS, Kath JC, Jones LH, Burlingame AL, Taunton J Journal of the American Chemical Society, 139(2), 680, 2017 |
5 |
Phase separation of signaling molecules promotes T cell receptor signal transduction Su XL, Ditlev JA, Hui EF, Xing WM, Banjade S, Okrut J, King DS, Taunton J, Rosen MK, Vale RD Science, 352(6285), 595, 2016 |
6 |
Design of Reversible, Cysteine-Targeted Michael Acceptors Guided by Kinetic and Computational Analysis Krishnan S, Miller RM, Tian BX, Mullins RD, Jacobson MP, Taunton J Journal of the American Chemical Society, 136(36), 12624, 2014 |
7 |
Design of Reversible, Cysteine-Targeted Michael Acceptors Guided by Kinetic and Computational Analysis (vol 136, pg 12624, 2014) Krishnan S, Miller RM, Tian BX, Mullins RD, Jacobson MP, Taunton J Journal of the American Chemical Society, 136(50), 17690, 2014 |
8 |
Electrophilic Fragment-Based Design of Reversible Covalent Kinase Inhibitors Miller RM, Paavilainen VO, Krishnan S, Serafimova IM, Taunton J Journal of the American Chemical Society, 135(14), 5298, 2013 |
9 |
Selective Targeting of Distinct Active Site Nucleophiles by Irreversible Src-Family Kinase Inhibitors Gushwa NN, Kang SM, Chen J, Taunton J Journal of the American Chemical Society, 134(50), 20214, 2012 |
10 |
Total synthesis and biological mode of action of largazole: A potent Class I histone deacetylase inhibitor Bowers A, West N, Taunton J, Schreiber SL, Bradner JE, Williams RM Journal of the American Chemical Society, 130(33), 11219, 2008 |