검색결과 : 10건
| No. | Article |
|---|---|
| 1 |
Small molecule inhibition of the KRAS-PDE delta interaction impairs oncogenic KRAS signalling Zimmermann G, Papke B, Ismail S, Vartak N, Chandra A, Hoffmann M, Hahn SA, Triola G, Wittinghofer A, Bastiaens PIH, Waldmann H Nature, 497(7451), 638, 2013 |
| 2 |
Synthesis of functional Ras lipoproteins and fluorescent derivatives Kuhn K, Owen DJ, Bader B, Wittinghofer A, Kuhlmann J, Waldmann H Journal of the American Chemical Society, 123(6), 1023, 2001 |
| 3 |
Structure of a Ran-binding domain complexed with Ran bound to a GTP analogue: implications for nuclear transport Vetter IR, Nowak C, Nishimoto T, Kuhlmann J, Wittinghofer A Nature, 398(6722), 39, 1999 |
| 4 |
The 1.7 angstrom crystal structure of the regulator of chromosome condensation (RCC1) reveals a seven-bladed propeller Renault L, Nassar N, Vetter I, Becker J, Klebe C, Roth M, Wittinghofer A Nature, 392(6671), 97, 1998 |
| 5 |
Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP de Rooij J, Zwartkruis FJT, Verheijen MHG, Cool RH, Nijman SMB, Wittinghofer A, Bos JL Nature, 396(6710), 474, 1998 |
| 6 |
The Ras-Rasgap Complex - Structural Basis for GTPase Activation and Its Loss in Oncogenic Ras Mutants Scheffzek K, Ahmadian MR, Kabsch W, Wiesmuller L, Lautwein A, Schmitz F, Wittinghofer A Science, 277(5324), 333, 1997 |
| 7 |
Crystal-Structure of the GTPase-Activating Domain of Human P120Gap and Implications for the Interaction with Ras Scheffzek K, Lautwein A, Kabsch W, Ahmadian MR, Wittinghofer A Nature, 384(6609), 591, 1996 |
| 8 |
Formation of a Transition-State Analog of the Ras GTPase Reaction by Ras-Center-Dot-GDP, Tetrafluoroaluminate, and GTPase-Activating Proteins Mittal R, Ahmadian MR, Goody RS, Wittinghofer A Science, 273(5271), 115, 1996 |
| 9 |
Crystal-Structure of the Nuclear Ras-Related Protein Ran in Its GDP-Bound Form Scheffzek K, Klebe C, Fritzwolf K, Kabsch W, Wittinghofer A Nature, 374(6520), 378, 1995 |
| 10 |
The 2.2-Angstrom Crystal-Structure of the Ras-Binding Domain of the Serine Threonine Kinase C-Raf1 in Complex with Rap1A and a GTP Analog Nassar M, Horn G, Herrmann C, Scherer A, Mccormick F, Wittinghofer A Nature, 375(6532), 554, 1995 |