화학공학소재연구정보센터
검색결과 : 10건
No. Article
1 CTLA-4 blockade drives loss of T-reg stability in glycolysis-low tumours
Zappasodi R, Serganova I, Cohen IJ, Maeda M, Shindo M, Senbabaoglu Y, Watson MJ, Leftin A, Maniyar R, Verma S, Lubin M, Ko M, Mane MM, Zhong H, Liu CL, Ghosh A, Abu-Akeel M, Ackerstaff E, Koutcher JA, Ho PC, Delgoffe GM, Blasberg R, Wolchok JD, Merghoub T
Nature, 591(7851), 652, 2021
2 Cancer immunotherapy using checkpoint blockade
Ribas A, Wolchok JD
Science, 359(6382), 1350, 2018
3 Chromatin states define tumour-specific T cell dysfunction and reprogramming
Philip M, Fairchild L, Sun L, Horste EL, Amara SC, Shakiba M, Scott AC, Viale A, Lauer P, Erghoub TM, Hellmann MD, Wolchok JD, Leslie CS, Schietinger A
Nature, 545(7655), 452, 2017
4 T-cell invigoration to tumour burden ratio associated with anti-PD-1 response
Huang AC, Postow MA, Orlowski RJ, Mick R, Bengsch B, Manne S, Xu W, Harmon S, Giles JR, Wenz B, Adamow M, Kuk D, Panageas KS, Carrera C, Wong P, Quagliarello F, Wubbenhorst B, D'Andrea K, Pauken KE, Herati RS, Staupe RP, Schenkel JM, McGettigan S, Kothari S, George SM, Vonderheide RH, Amaravadi RK, Karakousis GC, Schuchter LM, Xu XW, Nathanson KL, Wolchok JD, Gangadhar TC, Wherry EJ
Nature, 545(7652), 60, 2017
5 Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer
Balachandran VP, Luksza M, Zhao JN, Makarov V, Moral JA, Remark R, Herbst B, Askan G, Bhanot U, Senbabaoglu Y, Wells DK, Cary CIO, Grbovic-Huezo O, Attiyeh M, Medina B, Zhang J, Loo J, Saglimbeni J, Abu-Akeel M, Zappasodi R, Riaz N, Smoragiewicz M, Kelley ZL, Basturk O, Gonen M, Levine AJ, Allen PJ, Fearon DT, Merad M, Gnjatic S, Iacobuzio-Donahue CA, Wolchok JD, DeMatteo RP, Chan TA, Greenbaum BD, Merghoub T, Leach SD
Nature, 551(7681), 512, 2017
6 A neoantigen fitness model predicts tumour response to checkpoint blockade immunotherapy
Luksza M, Riaz N, Makarov V, Balachandran VP, Hellmann MD, Solovyov A, Rizvi NA, Merghoub T, Levine AJ, Chan TA, Wolchok JD, Greenbaum BD
Nature, 551(7681), 517, 2017
7 Overcoming resistance to checkpoint blockade therapy by targeting PI3K gamma in myeloid cells
De Henau O, Rausch M, Winkler D, Campesato LF, Liu CL, Hirschhorn-Cymerman D, Budhu S, Ghosh A, Pink M, Tchaicha J, Douglas M, Tibbitts T, Sharma S, Proctor J, Kosmider N, White K, Stern H, Soglia J, Adams J, Palombella VJ, McGovern K, Kutok JL, Wolchok JD, Merghoub T
Nature, 539(7629), 443, 2016
8 Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade
McGranahan N, Furness AJS, Rosenthal R, Ramskov S, Lyngaa R, Saini SK, Jamal-Hanjani M, Wilson GA, Birkbak NJ, Hiley CT, Watkins TBK, Shafi S, Murugaesu N, Mitter R, Akarca AU, Linares J, Marafioti T, Henry JY, Van Allen EM, Miao DN, Schilling B, Schadendorf D, Garraway LA, Makarov V, Rizvi NA, Snyder A, Hellmann MD, Merghoub T, Wolchok JD, Shukla SA, Wu CJ, Peggs KS, Chan TA, Hadrup SR, Quezada SA, Swanton C
Science, 351(6280), 1463, 2016
9 Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer
Rizvi NA, Hellmann MD, Snyder A, Kvistborg P, Makarov V, Havel JJ, Lee W, Yuan JD, Wong P, Ho TS, Miller ML, Rekhtman N, Moreira AL, Ibrahim F, Bruggeman C, Gasmi B, Zappasodi R, Maeda Y, Sander C, Garon EB, Merghoub T, Wolchok JD, Schumacher TN, Chan TA
Science, 348(6230), 124, 2015
10 CANCER Antitumour immunity gets a boost
Wolchok JD, Chan TA
Nature, 515(7528), 496, 2014