| 1 |
Cysteine in cell culture media induces acidic IgG1 species by disrupting the disulfide bond network
Prade E, Zeck A, Stiefel F, Unsoeld A, Mentrup D, Gutierrez EA, Gorr IH
Biotechnology and Bioengineering, 118(3), 1091, 2021 |
| 2 |
Multi-omics profiling of a CHO cell culture system unravels the effect of culture pH on cell growth, antibody titer, and product quality
Lee AP, Kok YJ, Lakshmanan M, Leong D, Zheng L, Lim HL, Chen SW, Mak SY, Ang KS, Templeton N, Salim T, Wei XN, Gifford E, Tan AHM, Bi XZ, Ng SK, Lee DY, Ling WLW, Ho YS
Biotechnology and Bioengineering, 118(11), 4305, 2021 |
| 3 |
Design of experiments as a valuable tool for biopharmaceutical analysis with (imaged) capillary isoelectric focusing
Kahle J, Stein M, Watzig H
Electrophoresis, 40(18-19), 2382, 2019 |
| 4 |
Industrial bioprocessing perspectives on managing therapeutic protein charge variant profiles
Chung S, Tian J, Tan ZJ, Chen J, Lee JC, Borys M, Li ZJ
Biotechnology and Bioengineering, 115(7), 1646, 2018 |
| 5 |
Coupling imaged capillary isoelectric focusing with mass spectrometry using a nanoliter valve
Montealegre C, Neususs C
Electrophoresis, 39(9-10), 1151, 2018 |
| 6 |
Determination of protein charge variants with (imaged) capillary isoelectric focusing and capillary zone electrophoresis
Kahle J, Watzig H
Electrophoresis, 39(20), 2492, 2018 |
| 7 |
High-resolution separation of monoclonal antibodies mixtures and their charge variants by an alternative and generic CZE method
Goyoni A, Francois YN, Colas O, Beck A, Veuthey JL, Guillarme D
Electrophoresis, 39(16), 2083, 2018 |
| 8 |
Enhanced product understanding in the QbD paradigm: linkage between charge heterogeneity and stability of monoclonal antibody therapeutic products
Joshi VS, Kumar V, Rathore AS
Journal of Chemical Technology and Biotechnology, 93(8), 2102, 2018 |
| 9 |
Characterization of human hybrid cell line, F2N78, through a comparison of culture performances and protein qualities
Seo JS, Min BS, Kim YJ, Cho JM, Kwon GS, Lim BP, Chang SJ, Kim DI
Biotechnology Letters, 39(4), 501, 2017 |
| 10 |
Evaluation of Heavy Chain C-Terminal Deletions on Productivity and Product Quality of Monoclonal Antibodies in Chinese Hamster Ovary (CHO) Cells
Hu ZL, Tang DM, Misaghi S, Jiang GY, Yu C, Yim M, Shaw D, Snedecor B, Laird MW, Shen A
Biotechnology Progress, 33(3), 786, 2017 |
