The behaviour of neutral phosphine oxides Cyanex-921, Cyanex-923 and Cyanex-925 in the extraction of Pb(II) from nitrate media is described. The extraction of Pb(II) was found to be quantitative in the pH range 8.0-9.0 with these extractants. From the metal loaded organic phases for these extractants, Pb(II) was stripped back with 0.5 M H2SO4. The effects of pH, temperature, equilibrium time, diluents, diverse ions and stripping ability using various acids on the extraction of Pb(II) have been studied. The methods are also extended for the analysis of real samples.