Multi-phase simulations of turbulent driven flow in a dense medium cyclone with magnetite medium have been conducted in Fluent, using the Algebraic Slip Mixture model to model the dispersed phases and the air-core, and both the Large Eddy Simulation turbulence model (LES) and Reynolds Stress Models (RSM) for turbulence closure. The predicted air-core shape and diameter were found to be close to the experimental results measured by gamma ray tomography. It is possible to use the LES turbulence model with ASM multi-phase model to predict the air/slurry interface accurately. Multi-phase simulations (air/water/medium) show appropriate medium segregation effects but over-predict the level of segregation compared to that measured by gamma ray tomography near the wall. This is believed to be because of unaccounted back-mixing of the dispersed phase due to turbulence in the basic Algebraic Slip Mixture model. The predictions of accurate axial segregation of magnetite medium are investigated using the LES turbulence model in conjunction with the multi-phase mixture model and viscosity corrections according to the feed particle loading factor. At higher feed densities the agreement between the Dunglison [Dunglison, M.E., 1999, A general model of the dense medium cylone, PhD thesis, JKMRC, University of Queensland] correlations and experimental measurements and the CFD is reasonably good, but the overflow density is lower than the model predictions. It is believed that the excessive underflow volumetric flow rates are responsible for under prediction of the overflow density. The effect of size distribution of the magnetite has been fully studied. As expected, the ultra-fine magnetite sizes (i.e. 2 and 7 microns) are distributed uniformly throughout the cyclone. As the size of magnetite increases, more segregation of magnetite occurs close to the wall. (c) 2006 Elsevier B.V. All rights reserved.