This study compared tensile bond strengths between conventional compression-molded heat (HC)-, auto (AP)-, and microwave-polymerized (MC) poly(methyl methacrylate)-based denture resins and a relatively new injection-molded, microwave-polymerized polyurethane based resin (MI) bonded to a highly cross-linked denture tooth. In the first part of the experiments, denture teeth were used as received. In the second part, they were treated with dichloromethane to see its effect on bonding of conventional denture bases (HCS and APS). Bond strength was tested in tension according to ADA specification No.15. The results showed that the HC group failed cohesively because of higher interface bonding (49.95MPa) compared with those of the others (AP: 25.41MPa; MC: 22.06MPa; MI: 20.02MPa). The application of dichloromethane improved bond strengths of HCS and APS groups (60.61 and 32.03MPa, respectively). It was suggested that dichloromethane could be applied on the denture teeth ridge lap area prior to denture base processing to enhance adhesion between the tooth/resin.