It has been acknowledged that infill drilling can improve the recovery of hydrocarbons by accelerating production as most reservoirs in the world are not homogeneous. With the increasing demand for energy and higher oil and gas prices, more and more fields all over the world are undergoing infill drilling. This paper discusses two recently developed techniques to determine the infill drilling potential in large tight gas reservoirs and it summarizes what petroleum engineers have learnt about the application of those two techniques. Field examples are also included in this paper to demonstrate the usefulness, as well as the limitations, of these techniques to help independent operators develop operation and design strategies for current and future infill drilling projects in large tight gas basins.