Densities, refractive indices, and speeds of sounds at 298.15 K, and isobaric vapor-liquid equilibria data at 101.3 kPa were reported for the binary mixtures containing methanol + ethyl butyrate and vinyl acetate + ethyl butyrate. Excess molar volumes, refractive index deviations, and changes of speed sound on mixing were calculated from the measurement results and fitted with Redlich-Kister polynomials. VLE experimental data were satisfactorily tested for thermodynamic consistency by means of a modified Dechema test. The activity coefficients were correlated with the Margules, van Laar, UNIQUAC, NRTL, and Wilson equations. The ASOG model was also used for prediction.