The solubility of D- p- hydroxyphenylglycine in water, methanol, ethanol, carbon tetrachloride, toluene, and N, Ndimethylformamide ( DMF) between 278 K and 323 K was measured using a laser monitoring observation technique. Results of these measurements were correlated with a semiempirical equation. For the six groups of data studied, the semiempirical equation provided an accurate mathematical representation of the experimental data.