This work presents experimental data of systems composed of grape seed oil + oleic acid + ethanol + water from (283.2 to 298.2) K. The solvent selectivity and oleic acid distribution coefficient were more affected by water content in the alcoholic solvent than by temperature. The enhancement of the water content in the solvent and the reduction of temperature within the studied ranges led to greater values of solvent selectivity. Nevertheless, greater oleic acid distribution coefficients were found as a result of the reductions in temperature and water content in the solvent.