The mole fraction solubility of vinyl chloride in 1-butyl-3-methyl imidazolium tetrafluoroborate ([BMIM][BF(4)]), 1-butyl-3-methyl imidazolium hexafluorophosphate ([BMIM][PF(6)]), 2,4-bis(2-hydroxypropyl)-1,1,3,3-tetramethyl guanidinium tetrafluoroborate ([TMGHPO(2)][BF(4)]), and tetramethyl guanidinelactate (TMGL) is reported as a function of temperature at (293.15, 313.15, and 333.15) K at pressures of up to 2 bar on the basis of a saturation method. The Henry's law constants and enthalpy of solution of vinyl chloride were calculated from the solubility data. The enthalpy of solution is negative for all mixtures.