The solubility of (RS)-2-(2-fluorobipheny1-4-yl)propanoic acid (flurbiprofen) in supercritical carbon dioxide and in a mixed solvent consistma of carbon dioxide and methanol at (303.15 and 313 15) K between the pressures of (10.0 and 20 0) MPa is reported The solubilities were measured using a direct visualization technique The experimental data is described using the Peng Robinson equation of state (PR EoS) together with a one-parameter van del Waals mixing rule