Gas hydrate formation is undesired in processing and gas distribution. Therefore, it is important to have a thermodynamic model that predicts correctly gas hydrate formation. Hydrate formation is very well studied in the literature in the presence of liquid water, and hydrate thermodynamic models predict correctly its formation; however, there is little information about gas hydrate formation without an aqueous phase. The new experimental procedure combining an equilibrium cell with water measurement by a Karl Fischer coulometer developed in our previous work (Youssef et al. Ind. Eng. Chem. Res. 2009, 48, 4045-4050) was used to determine the hydrate dissociation temperature in the absence of an aqueous phase on three gas mixtures at different pressures and for different amounts of water content. As in previous work, the classical Platteeuw and van der Waals model associated to the cubic plus association (CPA) equation of state, used in a totally predictive way, correctly predict hydrate dissociation with or without an aqueous phase for the gas mixtures.