Isothermal vapor liquid equilibrium data of the 1,1,2,2-tetrafluoroethane (R134) + fluoroethane (R161) system were measured at temperatures ranging from (263.15 to 288.15) K with an apparatus using a recirculation method. The experimental data including temperatures, pressures, and compositions were regressed using the Peng-Robinson equation of state with the Huron-Vidal mixing rule involving the nonrandom two-liquid (NRTL) model. No azeotropic behavior was found in the measured temperature points.