The solubility of 6-chloropyridazin-3-amine in methanol, ethanol, n-butanol, N,N-dimethylformamide, acetone, cyclohexanone, ethyl acetate, and toluene at temperatures ranging from (298.15 to 343.55) K at atmospheric pressure was obtained using a synthetic method. The results showed that the solubility of 6-chloropyridazin-3-amine in these solvents increases with rising temperature. The modified Apelblat equation and 211 equation were used to correlate the experimental solubility respectively. The calculated values with equations showed good consistency with the experimental values, and the root-mean-square relative deviation was less than 4.68 %. The enthalpy of dissolution and entropy of 6-chloropyridazin-3-amine were obtained by the van't Hoff equation, and the change in Gibbs free energy was calculated.