Vapor liquid equilibrium data of the binary mixtures nitrogen + acetone and oxygen + acetone are measured and compared to available experimental data from the literature. The saturated liquid line is determined for both systems at specified temperature and liquid phase composition in a high-pressure view cell with a synthetic method. For nitrogen + acetone, eight isotherms between 223 K and 400 K up to a pressure of 12 MPa are measured. For oxygen + acetone, two isotherms at 253 K and 283 K up to a pressure of 0.75 MPa are measured. Thereby, the maximum content of the gaseous component in the saturated liquid phase is 0.06 mol/mol (nitrogen) and 0.006 mol/mol (oxygen), respectively. On the basis of these data, the Henry's law constant is calculated. In addition, the saturated vapor line of nitrogen + acetone is studied at specified temperature and pressure with an analytical method. Three isotherms between 303 K and 343 K up to a pressure of 1.8 MPa are measured. All present data are compared to the available experimental data. Finally, the Peng-Robinson equation of state with the quadratic mixing rule and the Huron-Vidal mixing rule is adjusted to the present experimental data for both systems.